wxPython is a blending of the WxWidgets (formerly WxWindows) class library for C++ and Python. wxPython can be found at (surprise!) http://www.wxpython.org/ and it has its own wiki there: http://wiki.wxpython.org/. ShowMeDo has a collection of [http://showmedo.com/videos/series?name=PythonWxPythonBeginnersSeries introductory wxPython videos].
IgorTamara: WxPython in a [http://www.debian.org good linux distribution] is really easy to install, just : apt-get install libwxgtk2.4-python or
MythDebunking: WxPython is hard to install on Unix. You need the right versions of GTK, WxWidgets and WxPython.
Also check the WxDesigner and BoaConstructor.