Twisted is too big and there are too many small groups of people who want to work on different things for a "Twisted Sprint" to be meaningful. There will be several mini-sprints involving improvements to the Twisted and related code base. Tentatively, these will be the mini-sprints:
NewPB - lead by BrianWarner. Probably a few days of this.
Reality - lead by ChristopherArmstrong. At least one full day of this.
Releasing automation - lead by ChristopherArmstrong. Is someone else willing to help me?
HTTP server - lead by ItamarShtullTrauring