See also GuiProgramming for a full list of toolkits.

pyFLTK

• pyFLTK is based on FLTK

• cross-platform
• small and fast
• access to OpenGL

Pygame

• you are in full control
• you are responsible for everything
• only one window

PyGTK

• powerful - aims to be a 1:1 GTK wrapper
• good GTK docs out there for both C and Python
• it's a wrapper - sometimes C idioms leak through

Pyglet

• new
• OpenGL-y (3D)

PyQT

PythonCard

Tkinter

• batteries included
• ugh

wxPython

• cross platform
• doesn't always look the same though