Here is a list of known Python-based WikiEngines
Hatta -- a Wiki which runs out of a Mercurial repository whose pages are just the files in that repository
Markdoc -- a lightweight Markdown-based Wiki system, public domain
Pyle -- GPL wiki with multiple VCS backends, email notifications, edit by FTP and lot of other features
sahriswiki -- Mercurial backend support, plugins, MIT licensed.
Smug - GPLed content editing system with moderation queue.
Sphene Community Tools -- Django based wiki and forum applications.
Trac -- an enhanced wiki, issue tracking and source code browser system. Supports multiple markup formats including MoinMoin, reStructuredText, html, and textile. Runs as FastCGI, WSGI or standalone. Pluggable architecture with focus on simplicity.
zim-wiki - WYSIWIG personal/desktop wiki with index, links, image inclusion, checkboxes and bulleted lists, equations, graphviz; calendar, ToDo; prints to clean html. Customizable, all-python over gtk2, inbuilt-server, uses filesystem as db; debian packaged. Documentation. Actively developed 2012.
Archaeology (dead, missing and outdated)
CyberPublishing -- a wiki-based web publishing framework written in Python; GPL
Luminotes -- a WYSIWYG personal wiki notebook for organizing your notes and ideas. Not currently developed.
PikiPiki -- Python-based, completely standalone, GPL, famous ancestor of most Python wikies