Pyjamas-Desktop is a cross-platform framework and applications widget set, based on [http://webkit.org WebKit]. PyWebkitGtk is currently the basis for Pyjamas-Desktop, and it is conceivable that there will exist a PyWebkitQt4, and Pyjamas-Desktop will run on top of that, as well.
[http://code.google.com/p/pyjamas Pyjamas]