PyKDE
PyKDE, written and actively maintained by Jim Bublitz, is a full interface to KDE's libraries. This allows you to write fully-fledged KDE applications with python.
PyKDE needs PyQt and ["SIP"] to run. These are both actively maintained by Phil Thompson.
More information is available at [http://riverbankcomputing.co.uk/pykde/].
If you have written an application for PyKDE, please list it here:
IoSlavesTutorial (see also [http://www.boddie.org.uk/david/Projects/Python/KDE/index.html Writing IOSlaves in Python])