MacPython can drive many Mac apps (mostly with the [[../AppscriptModule]]).  
Here are links to the collected (but sometimes incomplete) wisdom contained in the wiki about such stuff:

  * Apple
    * [[../iCal]]
    * [[../iPhoto]]
    * [[../iTunes]]
    * [[../FileMakerPro]]
    * [[../TextEdit]]
  * Adobe
    * [[../InDesign]]
    * [[../PhotoShop]]
  * Other
    * [[../iTerm]]
    * [[../VoodooPad]]
    * [[../Growl]]
    * [[../QuarkXPress]]
    * [[../MediaPro]]
    * [[../OmniGraffle]]
    * [[../SoundtrackPro]]