Pyglet
- new
- OpenGL-y (3D)
PyQt
- Wraps Qt
- Not just GUI features
PySide
- Wraps Qt
Api compatible with PyQt
- LGPL License
PythonCard
- Wraps WX
- Easy to use
- Graphic widget insertion
- Slightly slow
Tkinter
- standard GUI toolkit included with Python
- simple and easy
wxPython
- cross platform
- doesn't always look the same though